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Aging- and activation-induced platelet microparticles suppress apoptosis in monocytic cells and differentially signal to proinflammatory mediator release

Background: Platelet microparticles (PM) are the most abundant cell-derived microparticles in the blood, and accumulate in thrombo-inflammatory diseases. Platelets produce PM upon aging via an apoptosis-like process and by activation with strong agonists. We previously showed that long-term treatmen...

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Autori principali: Vasina, Elena M, Cauwenberghs, Sandra, Staudt, Mareike, Feijge, Marion AH, Weber, Christian, Koenen, Rory R, Heemskerk, Johan WM
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3649808/
https://ncbi.nlm.nih.gov/pubmed/23675563
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