Link between Cancer and Alzheimer Disease via Oxidative Stress Induced by Nitric Oxide-Dependent Mitochondrial DNA Overproliferation and Deletion

Nitric oxide- (NO-) dependent oxidative stress results in mitochondrial ultrastructural alterations and DNA damage in cases of Alzheimer disease (AD). However, little is known about these pathways in human cancers, especially during the development as well as the progression of primary brain tumors...

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Detalhes bibliográficos
Main Authors: Aliev, Gjumrakch, Obrenovich, Mark E., Tabrez, Shams, Jabir, Nasimudeen R., Reddy, V. Prakash, Li, Yi, Burnstock, Geoffrey, Cacabelos, Ramon, Kamal, Mohammad Amjad
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3649749/
https://ncbi.nlm.nih.gov/pubmed/23691268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/962984
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