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Estimating Selection on Synonymous Codon Usage from Noisy Experimental Data

A key goal in molecular evolution is to extract mechanistic insights from signatures of selection. A case study is codon usage, where despite many recent advances and hypotheses, two longstanding problems remain: the relative contribution of selection and mutation in determining codon frequencies an...

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Detalhes bibliográficos
Main Authors: Wallace, Edward W.J., Airoldi, Edoardo M., Drummond, D. Allan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3649678/
https://ncbi.nlm.nih.gov/pubmed/23493257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/mst051
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