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Isoniazid resistance without a loss of fitness in Mycobacterium tuberculosis

The emergence of multi- and extensively drug-resistant tuberculosis (MDR-TB and XDR-TB, respectively) has intensified the critical public health implications of this global disease. The fitness of Mycobacterium tuberculosis (M.tb.) strains exhibiting MDR and XDR phenotypes is of fundamental importan...

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Detalles Bibliográficos
Main Authors: Lee, Jong-Hee, Ammerman, Nicole C., Nolan, Scott, Geiman, Deborah E., Lun, Shichun, Guo, Haidan, Bishai, William R.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648870/
https://ncbi.nlm.nih.gov/pubmed/22434196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1724
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