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Thrombin, a mediator of cerebrovascular inflammation in AD and hypoxia
Considerable evidence implicates hypoxia and vascular inflammation in Alzheimer's disease (AD). Thrombin, a multifunctional inflammatory mediator, is demonstrable in the brains of AD patients both in the vessel walls and senile plaques. Hypoxia-inducible factor 1α (HIF-1α), a key regulator of t...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3648692/ https://ncbi.nlm.nih.gov/pubmed/23675346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2013.00019 |
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