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Bayesian methods for meta-analysis of causal relationships estimated using genetic instrumental variables
Genetic markers can be used as instrumental variables, in an analogous way to randomization in a clinical trial, to estimate the causal relationship between a phenotype and an outcome variable. Our purpose is to extend the existing methods for such Mendelian randomization studies to the context of m...
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Main Authors: | , |
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Format: | Artigo |
Language: | Inglês |
Published: |
2010
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3648673/ https://ncbi.nlm.nih.gov/pubmed/20209660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.3843 |
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