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Bayesian methods for meta-analysis of causal relationships estimated using genetic instrumental variables

Genetic markers can be used as instrumental variables, in an analogous way to randomization in a clinical trial, to estimate the causal relationship between a phenotype and an outcome variable. Our purpose is to extend the existing methods for such Mendelian randomization studies to the context of m...

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Bibliographic Details
Main Authors: Burgess, Stephen, Thompson, Simon G.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648673/
https://ncbi.nlm.nih.gov/pubmed/20209660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.3843
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