Phenotypes of Allo- and Autoimmune Antibody Responses to FVIII Characterized by Surface Plasmon Resonance

Evidence of antibody isotype/subtype switching may provide prognostic value regarding the state of immune responses to therapeutic proteins, e.g. anti-factor VIII (FVIII) antibodies that develop in many hemophilia A patients, clinically termed “inhibitors”. A sensitive, high- information-content sur...

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Hlavní autoři: Lewis, Kenneth B., Hughes, Richard J., Epstein, Melinda S., Josephson, Neil C., Kempton, Christine L., Kessler, Craig M., Key, Nigel S., Howard, Tom E., Kruse-Jarres, Rebecca, Lusher, Jeanne M., Walsh, Christopher E., Watts, Raymond G., Ettinger, Ruth A., Pratt, Kathleen P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648518/
https://ncbi.nlm.nih.gov/pubmed/23667433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061120
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