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Low Concentrations of Metformin Selectively Inhibit CD133(+) Cell Proliferation in Pancreatic Cancer and Have Anticancer Action

Pancreatic cancer is the fourth leading cause of cancer related deaths in the United States. The prognosis remains dismal with little advance in treatment. Metformin is a drug widely used for the treatment of type II diabetes. Recent epidemiologic data revealed that oral administration of metformin...

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Hlavní autoři: Gou, Shanmiao, Cui, Pengfei, Li, Xiangsheng, Shi, Pengfei, Liu, Tao, Wang, Chunyou
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648476/
https://ncbi.nlm.nih.gov/pubmed/23667692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063969
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