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A nuclear tyrosine phosphatase downregulates interferon-induced gene expression.

Alpha and gamma interferons rapidly induce several early response genes in primary human diploid fibroblasts. The transcription rates of these genes are maximal after 1 h of interferon treatment and return to basal levels within 8 h. Three different interferon-activated DNA-binding complexes (ISGF3,...

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Udgivet i:Mol Cell Biol
Principais autores: David, M, Grimley, P M, Finbloom, D S, Larner, A C
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364823/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8246969/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.12.7515-7521.1993
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