T Cells Target APOBEC3 Proteins in Human Immunodeficiency Virus Type 1-Infected Humans and Simian Immunodeficiency Virus-Infected Indian Rhesus Macaques

APOBEC3 proteins mediate potent antiretroviral activity by hypermutating the retroviral genome during reverse transcription. To counteract APOBEC3 and gain a replicative advantage, lentiviruses such as human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV) have evolved t...

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Detalhes bibliográficos
Main Authors: Champiat, Stéphane, Garrison, Keith E., Raposo, Rui André Saraiva, Burwitz, Benjamin J., Reed, Jason, Tandon, Ravi, York, Vanessa A., Newman, Laura P., Nimityongskul, Francesca A., Wilson, Nancy A., Almeida, Rafael R., Martin, Jeffrey N., Deeks, Steven G., Rosenberg, Michael G., Wiznia, Andrew A., Spotts, Gerald E., Pilcher, Christopher D., Hecht, Fredrick M., Ostrowski, Mario A., Sacha, Jonah B., Nixon, Douglas F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648095/
https://ncbi.nlm.nih.gov/pubmed/23536679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00579-12
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