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Activation of the mouse mdr3 gene by insertion of retroviruses in multidrug-resistant P388 tumor cells.

In multidrug-resistant (MDR) derivatives of the mouse lymphoid tumor P388, the emergence of MDR is associated with overexpression and transcriptional activation of the mdr3 gene, either in the absence of (P388/VCR-10) or concomitant with (P388/ADM-2) gene amplification. In both instances, Northern (...

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Detalhes bibliográficos
Main Authors: Lepage, P, Devault, A, Gros, P
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC364809/
https://ncbi.nlm.nih.gov/pubmed/8246958
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