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Different Mechanisms Regulate Productive Herpes Simplex Virus 1 (HSV-1) and HSV-2 Infections in Adult Trigeminal Neurons

Herpes simplex virus 1 (HSV-1) and HSV-2 establish latency in different neuronal subtypes (A5+ and KH10+) in murine trigeminal ganglia, results which correlate with restricted productive infection in these neurons in vitro. HSV-2 latency-associated transcript (LAT) contains a cis-acting regulatory e...

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Detalhes bibliográficos
Main Authors: Bertke, Andrea S., Ma, AyeAye, Margolis, Mathew S., Margolis, Todd P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648083/
https://ncbi.nlm.nih.gov/pubmed/23514893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00383-13
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