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Vaccination with the Recombinant Major Outer Membrane Protein Elicits Antibodies to the Constant Domains and Induces Cross-Serovar Protection against Intranasal Challenge with Chlamydia trachomatis

To determine the ability of the major outer membrane protein (MOMP) to elicit cross-serovar protection, groups of mice were immunized by the intramuscular (i.m.) and subcutaneous (s.c.) routes with recombinant MOMP (rMOMP) from Chlamydia trachomatis serovars D (UW-3/Cx), E (Bour), or F (IC-Cal-3) or...

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Detalhes bibliográficos
Main Authors: Tifrea, Delia F., Ralli-Jain, Pooja, Pal, Sukumar, de la Maza, Luis M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648024/
https://ncbi.nlm.nih.gov/pubmed/23478318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00734-12
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