Interaction of Leptospira interrogans with Human Proteolytic Systems Enhances Dissemination through Endothelial Cells and Protease Levels

We have recently reported the ability of Leptospira to capture plasminogen (PLG) and generate plasmin (PLA) bound on the microbial surface in the presence of exogenous activators. In this work, we examined the effects of leptospiral PLG binding for active penetration through the endothelial cell bar...

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Détails bibliographiques
Auteurs principaux: Vieira, Monica L., Alvarez-Flores, Miryam P., Kirchgatter, Karin, Romero, Eliete C., Alves, Ivy J., de Morais, Zenaide M., Vasconcellos, Silvio A., Chudzinski-Tavassi, Ana M., Nascimento, Ana L. T. O.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
Sujets:
Molecular Pathogenesis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648023/
https://ncbi.nlm.nih.gov/pubmed/23478319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00020-13
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