Interaction of Leptospira interrogans with Human Proteolytic Systems Enhances Dissemination through Endothelial Cells and Protease Levels

We have recently reported the ability of Leptospira to capture plasminogen (PLG) and generate plasmin (PLA) bound on the microbial surface in the presence of exogenous activators. In this work, we examined the effects of leptospiral PLG binding for active penetration through the endothelial cell bar...

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Detalhes bibliográficos
Main Authors: Vieira, Monica L., Alvarez-Flores, Miryam P., Kirchgatter, Karin, Romero, Eliete C., Alves, Ivy J., de Morais, Zenaide M., Vasconcellos, Silvio A., Chudzinski-Tavassi, Ana M., Nascimento, Ana L. T. O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648023/
https://ncbi.nlm.nih.gov/pubmed/23478319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00020-13
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