Interaction of Leptospira interrogans with Human Proteolytic Systems Enhances Dissemination through Endothelial Cells and Protease Levels

We have recently reported the ability of Leptospira to capture plasminogen (PLG) and generate plasmin (PLA) bound on the microbial surface in the presence of exogenous activators. In this work, we examined the effects of leptospiral PLG binding for active penetration through the endothelial cell bar...

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Hlavní autoři: Vieira, Monica L., Alvarez-Flores, Miryam P., Kirchgatter, Karin, Romero, Eliete C., Alves, Ivy J., de Morais, Zenaide M., Vasconcellos, Silvio A., Chudzinski-Tavassi, Ana M., Nascimento, Ana L. T. O.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Molecular Pathogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648023/
https://ncbi.nlm.nih.gov/pubmed/23478319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00020-13
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