A Competitive Infection Model of Hematogenously Disseminated Candidiasis in Mice Redefines the Role of Candida albicans IRS4 in Pathogenesis

Candida albicans IRS4 encodes a protein that regulates phosphatidylinositol-(4,5)-bisphosphate, which was shown to contribute to hematogenously disseminated candidiasis (DC) after several days in the standard mouse model. Our objective was to more accurately define the temporal contributions of IRS4...

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Detalhes bibliográficos
Main Authors: Raman, Suresh B., Nguyen, M. Hong, Cheng, Shaoji, Badrane, Hassan, Iczkowski, Kenneth A., Wegener, Marilyn, Gaffen, Sarah L., Mitchell, Aaron P., Clancy, Cornelius J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647996/
https://ncbi.nlm.nih.gov/pubmed/23429534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00743-12
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