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p53 Directly Represses Id2 to Inhibit the Proliferation of Neural Progenitor Cells

Neural progenitor cells (NPCs) have the capacity to proliferate and give rise to all major central nervous system cell types and represent a possible cell of origin in gliomagenesis. Deletion of the tumor suppressor gene Tp53 (p53) results in increased proliferation and self-renewal of NPCs and is a...

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Detalhes bibliográficos
Main Authors: Paolella, BR, Havrda, MC, Mantani, A, Wray, CM, Zhang, Z, Israel, MA
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647692/
https://ncbi.nlm.nih.gov/pubmed/21608079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.660
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