A Novel Rat Model of Type 2 Diabetes: The Zucker Fatty Diabetes Mellitus ZFDM Rat

The Zucker fatty (ZF) rat harboring a missense mutation (fatty, fa) in the leptin receptor gene (Lepr) develops obesity without diabetes; Zucker diabetic fatty (ZDF) rats derived from the ZF strain exhibit obesity with diabetes and are widely used for research on type 2 diabetes (T2D). Here we estab...

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Hauptverfasser: Yokoi, Norihide, Hoshino, Masayuki, Hidaka, Shihomi, Yoshida, Eri, Beppu, Masayuki, Hoshikawa, Ritsuko, Sudo, Katsuko, Kawada, Akihiko, Takagi, Sadaaki, Seino, Susumu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647587/
https://ncbi.nlm.nih.gov/pubmed/23671847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/103731
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