DNA topoisomerase I controls the kinetics of promoter activation and DNA topology in Saccharomyces cerevisiae.
Inactivation of the nonessential TOP1 gene, which codes for Saccharomyces cerevisiae DNA topoisomerase I, affects the rate of transcription starting at the ADH2 promoter. For both the chromosomal gene and the plasmid-borne promoter, mRNA accumulation is kinetically favored in the mutant relative to...
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| Publicado en: | Mol Cell Biol |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Taylor & Francis
1993
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364733/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8413266/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.11.6702-6710.1993 |
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