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Cardiac and Renal Protective Effects of Irbesartan via Peroxisome Proliferator‐Activated Receptorγ–Hepatocyte Growth Factor Pathway Independent of Angiotensin II Type 1a Receptor Blockade in Mouse Model of Salt‐Sensitive Hypertension

BACKGROUND: “Aldosterone breakthrough” observed in patients receiving long‐term treatment with angiotensin blockade is strongly associated with increased risk of left ventricular hypertrophy, poor exercise capacity, refractory proteinuria, and declining glomerular filtration rate through the profibr...

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Bibliografiset tiedot
Päätekijät: Kusunoki, Hiroshi, Taniyama, Yoshiaki, Rakugi, Hiromi, Morishita, Ryuichi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Publishing Ltd 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647265/
https://ncbi.nlm.nih.gov/pubmed/23608606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.113.000103
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