Structural and Hydrodynamic Analysis of a Novel Drug Delivery Vector: ELP[V(5)G(3)A(2)-150]

The therapeutic potential of elastin-like polypeptide (ELP) conjugated to therapeutic compounds is currently being investigated as an approach to target drugs to solid tumors. ELPs are hydrophobic polymers that are soluble at low temperatures and cooperatively aggregate above a transition temperatur...

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Detalhes bibliográficos
Main Authors: Lyons, Daniel F., Le, Vu, Bidwell, Gene L., Kramer, Wolfgang H., Lewis, Edwin A., Raucher, Drazen, Correia, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Proteins and Nucleic Acids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647178/
https://ncbi.nlm.nih.gov/pubmed/23663844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.03.040
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