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Isopeptide Bonds Mechanically Stabilize Spy0128 in Bacterial Pili

Pili on the surface of Streptococcus pyogenes play a crucial role in adhesion to and colonization in human cells. The major pilin subunit, Spy0128, features intramolecular covalent isopeptide bonds that autocatalytically form between the side chains of lysine and asparagine residues and are regarded...

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Detalles Bibliográficos
Main Authors: Wang, Bo, Xiao, Shijun, Edwards, Scott A., Gräter, Frauke
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647160/
https://ncbi.nlm.nih.gov/pubmed/23663848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.04.002
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