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Isopeptide Bonds Mechanically Stabilize Spy0128 in Bacterial Pili

Pili on the surface of Streptococcus pyogenes play a crucial role in adhesion to and colonization in human cells. The major pilin subunit, Spy0128, features intramolecular covalent isopeptide bonds that autocatalytically form between the side chains of lysine and asparagine residues and are regarded...

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Detalhes bibliográficos
Main Authors: Wang, Bo, Xiao, Shijun, Edwards, Scott A., Gräter, Frauke
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647160/
https://ncbi.nlm.nih.gov/pubmed/23663848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.04.002
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