Changing monoclonal antibody keeping unaltered the chemotherapy regimen in metastatic colorectal cancer patients: is efficacy maintained?

Monoclonal antibodies bevacizumab and cetuximab both improve overall survival (OS), progression free survival (PFS) and overall response rate (ORR) when combined with irinotecan-containing regimens. The optimal sequence of these monoclonal antibodies in combination with chemotherapy is controversial...

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Main Authors: Grande, Roberta, Gemma, Donatello, Sperduti, Isabella, Gelibter, Alain, Giampaolo, Maria Anna, Trombetta, Giorgio, Nelli, Fabrizio, Gamucci, Teresa
格式: Artigo
語言:Inglês
出版: Springer International Publishing AG 2013
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647091/
https://ncbi.nlm.nih.gov/pubmed/23667824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-2-185
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