A Unique Form of Haptoglobin Produced by Murine Hematopoietic Cells Supports B-cell Survival, Differentiation and Immune Response

Haptoglobin (Hp), an acute phase reactant and major hemoglobin-binding protein, has a unique role in host immunity. Previously, we demonstrated that Hp-deficient C57BL/6J mice exhibit stunted development of mature T- and B-cells resulting in markedly lower levels of antigen-specific IgG. The current...

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Main Authors: Huntoon, Kristin M., Russell, Lisa, Tracy, Erin, Barbour, Karen W., Li, Qingsheng, Shrikant, Protul A., Berger, Franklin G., Garrett-Sinha, Lee Ann, Baumann, Heinz
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646973/
https://ncbi.nlm.nih.gov/pubmed/23548836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2013.03.008
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