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Design of Hybrid Lipid/Retroviral-Like Particle Gene Delivery Vectors

Recombinant retroviruses provide highly efficient gene delivery and the potential for stable gene expression. The retroviral envelope protein, however, is the source of significant disadvantages such as immunogenicity, poor stability (half-life of transduction activity of 5-7 h at 37 °C for amphotro...

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Main Authors: Keswani, Rahul K., Pozdol, Ian M., Pack, Daniel W.
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646931/
https://ncbi.nlm.nih.gov/pubmed/23485145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300561y
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