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A Behavioral Paradigm to Evaluate Hippocampal Performance in Aged Rodents for Pharmacological and Genetic Target Validation

Aged-related cognitive ability is highly variable, ranging from unimpaired to severe impairments. The Morris water maze (a reliable tool for assessing memory) has been used to distinguish aged rodents that are superior learners from those that are learning impaired. This task, however, is not practi...

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Bibliografische gegevens
Hoofdauteurs: Gerstein, Hilary, Hullinger, Rikki, Lindstrom, Mary J., Burger, Corinna
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646843/
https://ncbi.nlm.nih.gov/pubmed/23667471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062360
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