The Natural Human IgM Antibody PAT-SM6 Induces Apoptosis in Primary Human Multiple Myeloma Cells by Targeting Heat Shock Protein GRP78

In contrast to other haematological malignancies, targeted immunotherapy has not entered standard treatment regimens for de novo or relapsed multiple myeloma (MM) yet. While a number of IgG-formatted monoclonal antibodies are currently being evaluated in clinical trials in MM, our study aimed to inv...

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Detalhes bibliográficos
Main Authors: Rasche, Leo, Duell, Johannes, Morgner, Charlotte, Chatterjee, Manik, Hensel, Frank, Rosenwald, Andreas, Einsele, Hermann, Topp, Max S., Brändlein, Stephanie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646784/
https://ncbi.nlm.nih.gov/pubmed/23667612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063414
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