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Retinoic acid induction of major histocompatibility complex class I genes in NTera-2 embryonal carcinoma cells involves induction of NF-kappa B (p50-p65) and retinoic acid receptor beta-retinoid X receptor beta heterodimers.

Retinoic acid (RA) treatment of human embryonal carcinoma (EC) NTera-2 (NT2) cells induces expression of major histocompatibility complex (MHC) class I and beta-2 microglobulin surface molecules. We found that this induction was accompanied by increased levels of MHC class I mRNA, which was attribut...

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Publicat a:Mol Cell Biol
Autors principals: Segars, J H, Nagata, T, Bours, V, Medin, J A, Franzoso, G, Blanco, J C, Drew, P D, Becker, K G, An, J, Tang, T
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364675/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8413217/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.10.6157-6169.1993
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