Genetic Associations With Toxicity-related Discontinuation of Aromatase Inhibitor Therapy for Breast Cancer

BACKGROUND: Up to 25% of patients discontinue adjuvant aromatase inhibitor (AI) therapy due to intolerable symptoms. Predictors of which patients will be unable to tolerate these medications have not been defined. We hypothesized that inherited variants in candidate genes are associated with treatme...

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Detalhes bibliográficos
Main Authors: Henry, N. Lynn, Skaar, Todd C., Dantzer, Jessica, Li, Lang, Kidwell, Kelley, Gersch, Christina, Nguyen, Anne T., Rae, James M., Desta, Zeruesenay, Oesterreich, Steffi, Philips, Santosh, Carpenter, Janet S., Storniolo, Anna M., Stearns, Vered, Hayes, Daniel F., Flockhart, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646626/
https://ncbi.nlm.nih.gov/pubmed/23546553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-013-2504-3
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