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Cisplatin upregulates MSH2 expression by reducing miR-21 to inhibit A549 cell growth
miR-21 can act as an oncogene. MSH2 has been reported that it involved in the DNA mismatch repair (MMR) system and overexpression of MSH2 can induce cell apoptosis. We predicted that MSH2-3′-untranslated region (3′-UTR) was targeted by miR-21 using microRNA analysis softwares. To further explore the...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3646586/ https://ncbi.nlm.nih.gov/pubmed/23485110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopha.2012.11.008 |
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