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Regulated degradation of ornithine decarboxylase requires interaction with the polyamine-inducible protein antizyme.

Intracellular degradation of vertebrate ornithine decarboxylase (ODC) is accelerated by polyamines, the products of the pathway controlled by ODC. Antizyme, a reversible, tightly binding protein inhibitor of ODC activity, is believed to be involved in this process. Mouse and Trypanosoma brucei ODCs...

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Publicat a:Mol Cell Biol
Autors principals: Li, X, Coffino, P
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364621/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1630460/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.8.3556-3562.1992
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