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A diffusion-compensated model for the analysis of DCE-MRI data: theory, simulations, and experimental results

Accurate quantification of pharmacokinetic parameters in dynamic contrast-enhanced (DCE) MRI may be affected by the passive diffusion of contrast agent (CA) within the tissue. By introducing an additional term into the standard Tofts-Kety (STK) model, we correct for the effects of CA diffusion. We f...

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Detalhes bibliográficos
Main Authors: Fluckiger, Jacob U, Loveless, Mary E, Barnes, Stephanie L, Lepage, Martin, Yankeelov, Thomas E
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646091/
https://ncbi.nlm.nih.gov/pubmed/23458745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/0031-9155/58/6/1983
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