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4-Hydroxyhexenal (HHE) impairs glutamate transport in astrocyte cultures

Multiple studies show elevations of α, β-unsaturated aldehydic by-products of lipid peroxidation including 4-hydroxynonenal and acrolein in vulnerable brain regions of subjects throughout the progression of Alzheimer’s disease (AD). More recently 4-hydroxyhexenal (HHE), a diffusible α, β-unsaturated...

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Hlavní autoři: Lovell, Mark A., Bradley, Melissa A., Fister, Shuling X.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646088/
https://ncbi.nlm.nih.gov/pubmed/22766736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2012-120409
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