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Leading malignant cells initiate collective epithelial cell invasion in a three-dimensional heterotypic tumor spheroid model

Solid tumors consist of genetically and phenotypically diverse subpopulations of cancer cells with unique capacities for growth, differentiation, and invasion. While the molecular and microenvironmental bases for heterogeneity are increasingly appreciated, the outcomes of such intratumor heterogenei...

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Autors principals: Carey, Shawn P., Starchenko, Alina, McGregor, Alexandra L., Reinhart-King, Cynthia A.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646083/
https://ncbi.nlm.nih.gov/pubmed/23328900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-013-9565-x
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