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Environmental Oxygen Tension Regulates the Energy Metabolism and Self-Renewal of Human Embryonic Stem Cells

Energy metabolism is intrinsic to cell viability but surprisingly has been little studied in human embryonic stem cells (hESCs). The current study aims to investigate the effect of environmental O(2) tension on carbohydrate utilisation of hESCs. Highly pluripotent hESCs cultured at 5% O(2) consumed...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Forristal, Catherine E., Christensen, David R., Chinnery, Fay E., Petruzzelli, Raffaella, Parry, Kate L., Sanchez-Elsner, Tilman, Houghton, Franchesca D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645991/
https://ncbi.nlm.nih.gov/pubmed/23671606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062507
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