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Incorporating Genotype Uncertainties Into the Genotypic TDT for Main Effects and Gene-Environment Interactions

Genotype imputation has become a standard option for researchers to expand their genotype datasets to improve signal precision and power in tests of genetic association with disease. In imputations for family-based studies however, subjects are often treated as unrelated individuals: currently, only...

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Autors principals: Taub, Margaret A., Schwender, Holger, Beaty, Terri H., Louis, Thomas A., Ruczinski, Ingo
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645945/
https://ncbi.nlm.nih.gov/pubmed/22678881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21615
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