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Modification of the 85-kilodalton subunit of phosphatidylinositol-3 kinase in platelet-derived growth factor-stimulated cells.

The activated platelet-derived growth factor (PDGF) receptor physically associates with p85, a subunit of phosphatidylinositol-3 kinase. Although this interaction may activate phosphatidylinositol-kinase and is crucial for PDGF-induced mitogenesis, it has not been shown whether p85 is modified in th...

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Publicat a:Mol Cell Biol
Autors principals: Kavanaugh, W M, Klippel, A, Escobedo, J A, Williams, L T
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364590/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1321334/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.8.3415-3424.1992
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