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Loss of SUMOylation on ATF3 Inhibits Proliferation of Prostate Cancer Cells by Modulating CCND1/2 Activity

SUMOylation plays an important role in regulating a wide range of cellular processes. Previously, we showed that ATF3, a stress response mediator, can be SUMOylated and lysine 42 is the major SUMO site. However, the significance of ATF3 SUMOylation in biological processes is still poorly understood....

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Autores principales: Wang, Chiung-Min, Yang, Wei-Hsiung
Formato: Artigo
Lenguaje:Inglês
Publicado: Molecular Diversity Preservation International (MDPI) 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645748/
https://ncbi.nlm.nih.gov/pubmed/23591848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms14048367
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