Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins.

Alpha interferon stimulates transcription by converting the positive transcriptional regulator ISGF3 from a latent to an active form. This receptor-mediated event occurs in the cytoplasm, with subsequent translocation of the activated factor to the nucleus. ISGF3 has two components, termed ISGF3 alp...

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Bibliographic Details
Main Authors: Veals, S A, Schindler, C, Leonard, D, Fu, X Y, Aebersold, R, Darnell, J E, Levy, D E
Format: Artigo
Language:Inglês
Published: 1992
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC364572/
https://ncbi.nlm.nih.gov/pubmed/1630447
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