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SK4 Ca(2+) activated K(+) channel is a critical player in cardiac pacemaker derived from human embryonic stem cells

Proper expression and function of the cardiac pacemaker is a critical feature of heart physiology. Two main mechanisms have been proposed: (i) the “voltage-clock,” where the hyperpolarization-activated funny current I(f) causes diastolic depolarization that triggers action potential cycling; and (ii...

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Autors principals: Weisbrod, David, Peretz, Asher, Ziskind, Anna, Menaker, Nataly, Oz, Shimrit, Barad, Lili, Eliyahu, Sivan, Itskovitz-Eldor, Joseph, Dascal, Nathan, Khananshvili, Daniel, Binah, Ofer, Attali, Bernard
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645592/
https://ncbi.nlm.nih.gov/pubmed/23589888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221022110
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