Hammondia hammondi, an avirulent relative of Toxoplasma gondii, has functional orthologs of known T. gondii virulence genes

Toxoplasma gondii is a ubiquitous protozoan parasite capable of infecting all warm-blooded animals, including humans. Its closest extant relative, Hammondia hammondi, has never been found to infect humans and, in contrast to T. gondii, is highly attenuated in mice. To better understand the genetic b...

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Bibliographic Details
Main Authors: Walzer, Katelyn A., Adomako-Ankomah, Yaw, Dam, Rachel A., Herrmann, Daland C., Schares, Gereon, Dubey, Jitender P., Boyle, Jon P.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2013
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645575/
https://ncbi.nlm.nih.gov/pubmed/23589877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304322110
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