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Hammondia hammondi, an avirulent relative of Toxoplasma gondii, has functional orthologs of known T. gondii virulence genes

Toxoplasma gondii is a ubiquitous protozoan parasite capable of infecting all warm-blooded animals, including humans. Its closest extant relative, Hammondia hammondi, has never been found to infect humans and, in contrast to T. gondii, is highly attenuated in mice. To better understand the genetic b...

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Main Authors: Walzer, Katelyn A., Adomako-Ankomah, Yaw, Dam, Rachel A., Herrmann, Daland C., Schares, Gereon, Dubey, Jitender P., Boyle, Jon P.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645575/
https://ncbi.nlm.nih.gov/pubmed/23589877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304322110
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