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Repurposing the antimycotic drug flucytosine for suppression of Pseudomonas aeruginosa pathogenicity

Although antibiotic resistance represents a public health emergency, the pipeline of new antibiotics is running dry. Repurposing of old drugs for new clinical applications is an attractive strategy for drug development. We used the bacterial pathogen Pseudomonas aeruginosa as a target for the screen...

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Huvudupphovsmän: Imperi, Francesco, Massai, Francesco, Facchini, Marcella, Frangipani, Emanuela, Visaggio, Daniela, Leoni, Livia, Bragonzi, Alessandra, Visca, Paolo
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645532/
https://ncbi.nlm.nih.gov/pubmed/23569238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222706110
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