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Repurposing the antimycotic drug flucytosine for suppression of Pseudomonas aeruginosa pathogenicity

Although antibiotic resistance represents a public health emergency, the pipeline of new antibiotics is running dry. Repurposing of old drugs for new clinical applications is an attractive strategy for drug development. We used the bacterial pathogen Pseudomonas aeruginosa as a target for the screen...

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Detalhes bibliográficos
Main Authors: Imperi, Francesco, Massai, Francesco, Facchini, Marcella, Frangipani, Emanuela, Visaggio, Daniela, Leoni, Livia, Bragonzi, Alessandra, Visca, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645532/
https://ncbi.nlm.nih.gov/pubmed/23569238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222706110
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