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Effect of repetitive daily ethanol intoxication on adult rat brain: Significant changes in phospholipase A2 enzyme levels in association with increased PARP-1 indicate neuroinflammatory pathway activation

Collaborating on studies of subchronic daily intoxication in juvenile and adult rats, we examined whether the repetitive ethanol treatments at these two life stages altered levels of key neuroinflammation-associated proteins—aquaporin-4 (AQP4), certain phospholipase A2 (PLA2) enzymes, PARP-1 and cas...

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Detalhes bibliográficos
Main Authors: Tajuddin, Nuzhath F., Przybycien-Szymanska, Magdalena M., Pak, Toni R., Neafsey, Edward J., Collins, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645488/
https://ncbi.nlm.nih.gov/pubmed/23102656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.alcohol.2012.09.003
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