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Role of protein kinase C in T-cell antigen receptor regulation of p21ras: evidence that two p21ras regulatory pathways coexist in T cells.

T-lymphocyte activation via the antigen receptor complex (TCR) results in accumulation of p21ras in the active GTP-bound state. Stimulation of protein kinase C (PKC) can also activate p21ras, and it has been proposed that the TCR effect on p21ras occurs as a consequence of TCR regulation of PKC. To...

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Udgivet i:Mol Cell Biol
Principais autores: Izquierdo, M, Downward, J, Graves, J D, Cantrell, D A
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364544/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1620132/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.7.3305-3312.1992
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