CYP24A1 inhibition facilitates the anti-tumor effect of vitamin D3 on colorectal cancer cells

AIM: The effects of vitamin D3 have been investigated on various tumors, including colorectal cancer (CRC). 25-hydroxyvitamin-D3-24-hydroxylase (CYP24A1), the enzyme that inactivates the active vitamin D3 metabolite 1,25-dihydroxyvitamin D3 (1,25-D3), is considered to be the main enzyme determining...

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Autors principals: Kósa, János P, Horváth, Péter, Wölfling, János, Kovács, Dóra, Balla, Bernadett, Mátyus, Péter, Horváth, Evelin, Speer, Gábor, Takács, István, Nagy, Zsolt, Horváth, Henrik, Lakatos, Péter
Format: Artigo
Idioma:Inglês
Publicat: Baishideng Publishing Group Co., Limited 2013
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645380/
https://ncbi.nlm.nih.gov/pubmed/23674869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v19.i17.2621
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