Induction of the POU domain transcription factor Oct-2 during T-cell activation by cognate antigen.

Oct-2 is a transcription factor that binds specifically to octamer DNA motifs in the promoters of immunoglobulin and interleukin-2 genes. All tumor cell lines from the B-cell lineage and a few from the T-cell lineage express Oct-2. To address the role of Oct-2 in the T-cell lineage, we studied the e...

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Bibliographic Details
Main Authors: Kang, S M, Tsang, W, Doll, S, Scherle, P, Ko, H S, Tran, A C, Lenardo, M J, Staudt, L M
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC364529/
https://ncbi.nlm.nih.gov/pubmed/1620122
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