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The rate-limiting step in yeast PGK1 mRNA degradation is an endonucleolytic cleavage in the 3'-terminal part of the coding region.

Insertion of an 18-nucleotide-long poly(G) tract into the 3'-terminal untranslated region of yeast phosphoglycerate kinase (PGK1) mRNA increases its chemical half-life by about a factor of 2 (P. Vreken, R. Van der Veen, V. C. H. F. de Regt, A. L. de Maat, R. J. Planta, and H. A. Raué, Biochimie...

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Main Authors: Vreken, P, Raué, H A
Formato: Artigo
Idioma:Inglês
Publicado: 1992
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC364512/
https://ncbi.nlm.nih.gov/pubmed/1320194
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