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Lack of a significant role of P-Rex1, a major regulator of macrophage Rac1 activation and chemotaxis, in atherogenesis
BACKGROUND: Rho GTPases are known to play important roles in regulating multiple cellular processes that include cell polarization and migration. Among these Rho GTPases, Rac has been shown to be essential for F actin formation and cell migration. P-Rex1 is a Guanine Nucleotide Exchange Factor (GEF)...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3644862/ https://ncbi.nlm.nih.gov/pubmed/18502673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2008.04.001 |
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