Aspirin-Triggered Lipoxin A(4) Stimulates Alternative Activation of Microglia and Reduces Alzheimer Disease–Like Pathology in Mice

Microglia play an essential role in innate immunity, homeostasis, and neurotropic support in the central nervous system. In Alzheimer disease (AD), these cells may affect disease progression by modulating the buildup of β-amyloid (Aβ) or releasing proinflammatory cytokines and neurotoxic substances....

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Detalhes bibliográficos
Main Authors: Medeiros, Rodrigo, Kitazawa, Masashi, Passos, Giselle F., Baglietto-Vargas, David, Cheng, David, Cribbs, David H., LaFerla, Frank M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2013
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644736/
https://ncbi.nlm.nih.gov/pubmed/23506847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.01.051
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