Detection of HIV-1 Minority Variants Containing the K103N Drug-Resistance Mutation Using a Simple Method to Amplify RNA Targets (SMART)

The simple method for amplifying RNA targets (SMART) was used to detect K103N, a common HIV-1 reverse transcriptase drug-resistance mutation. Novel amplifiable SMART probes served as reporter molecules for RNA sequences that are captured and separated on a microfluidic platform under zero-flow condi...

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Main Authors: Morabito, Kenneth, Kantor, Rami, Tai, Warren, Schreier, Leeann, Tripathi, Anubhav
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2013
Assuntos:
Regular Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644729/
https://ncbi.nlm.nih.gov/pubmed/23541840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2013.02.005
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