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Bifidobacteria Stabilize Claudins at Tight Junctions and Prevent Intestinal Barrier Dysfunction in Mouse Necrotizing Enterocolitis

Whether intestinal barrier disruption precedes or is the consequence of intestinal injury in necrotizing enterocolitis (NEC) remains unknown. Using a neonatal mouse NEC model, we examined the changes in intestinal permeability and specific tight-junction (TJ) proteins preceding NEC and asked whether...

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Autors principals: Bergmann, Kelly R., Liu, Shirley X.L., Tian, Runlan, Kushnir, Anna, Turner, Jerrold R., Li, Hong-Lin, Chou, Pauline M., Weber, Christopher R., De Plaen, Isabelle G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644725/
https://ncbi.nlm.nih.gov/pubmed/23470164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.01.013
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